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Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies

PURPOSE: To activate and propagate populations of γδT cells expressing polyclonal repertoire of γ and δ TCR chains for adoptive immunotherapy for cancer, which has yet to be achieved. EXPERIMENTAL DESIGN: Clinical-grade artificial antigen presenting cells (aAPC) derived from K562 tumor cells were us...

詳細記述

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Deniger, Drew C., Maiti, Sourindra N., Mi, Tiejuan, Switzer, Kirsten C., Ramachandran, Vijaya, Hurton, Lenka V., Ang, Sonny, Olivares, Simon, Rabinovich, Brian A., Huls, Helen, Lee, Dean A., Bast, Robert C., Champlin, Richard E., Cooper, Laurence J.N.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233015/
https://ncbi.nlm.nih.gov/pubmed/24833662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3451
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