Tuning sensitivity of CAR to EGFR density limits recognition of normal tissue while maintaining potent anti-tumor activity

door Caruso, Hillary G., Hurton, Lenka V., Najjar, Amer, Rushworth, David, Ang, Sonny, Olivares, Simon, Mi, Tiejuan, Switzer, Kirsten, Singh, Harjeet, Huls, Helen, Lee, Dean A., Heimberger, Amy B., Champlin, Richard E., Cooper, Laurence J. N.
Gepubliceerd in Cancer Res (2015)

Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies

door Deniger, Drew C., Maiti, Sourindra N., Mi, Tiejuan, Switzer, Kirsten C., Ramachandran, Vijaya, Hurton, Lenka V., Ang, Sonny, Olivares, Simon, Rabinovich, Brian A., Huls, Helen, Lee, Dean A., Bast, Robert C., Champlin, Richard E., Cooper, Laurence J.N.
Gepubliceerd in Clin Cancer Res (2014)

Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells

door Hurton, Lenka V., Singh, Harjeet, Najjar, Amer M., Switzer, Kirsten C., Mi, Tiejuan, Maiti, Sourindra, Olivares, Simon, Rabinovich, Brian, Huls, Helen, Forget, Marie-Andrée, Datar, Vrushali, Kebriaei, Partow, Lee, Dean A., Champlin, Richard E., Cooper, Laurence J. N.
Gepubliceerd in Proc Natl Acad Sci U S A (2016)

Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations

door Deniger, Drew C., Yu, Jianqiang, Huls, M. Helen, Figliola, Matthew J., Mi, Tiejuan, Maiti, Sourindra N., Widhopf, George F., Hurton, Lenka V., Thokala, Radhika, Singh, Harjeet, Olivares, Simon, Champlin, Richard E., Wierda, William G., Kipps, Thomas J., Cooper, Laurence J. N.
Gepubliceerd in PLoS One (2015)