Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development

AIMS: β2-Spectrin is an actin-binding protein that plays an important role in membrane integrity and the transforming growth factor (TGF)-β signalling pathway as an adaptor for Smads. Loss of β2-spectrin in mice (Spnb2(−/−)) results in embryonic lethality with gastrointestinal, liver, neural, and he...

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Détails bibliographiques
Publié dans:Cardiovasc Res
Auteurs principaux: Lim, Jeong A., Baek, Hye Jung, Jang, Moon Sun, Choi, Eun Kyoung, Lee, Yong Min, Lee, Sang Jin, Lim, Sung Chul, Kim, Joo Young, Kim, Tae Hyun, Kim, Hye Sun, Mishra, Lopa, Kim, Sang Soo
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229887/
https://ncbi.nlm.nih.gov/pubmed/24064296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt222
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