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Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development
AIMS: β2-Spectrin is an actin-binding protein that plays an important role in membrane integrity and the transforming growth factor (TGF)-β signalling pathway as an adaptor for Smads. Loss of β2-spectrin in mice (Spnb2(−/−)) results in embryonic lethality with gastrointestinal, liver, neural, and he...
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Publicado no: | Cardiovasc Res |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229887/ https://ncbi.nlm.nih.gov/pubmed/24064296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt222 |
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