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Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development

AIMS: β2-Spectrin is an actin-binding protein that plays an important role in membrane integrity and the transforming growth factor (TGF)-β signalling pathway as an adaptor for Smads. Loss of β2-spectrin in mice (Spnb2(−/−)) results in embryonic lethality with gastrointestinal, liver, neural, and he...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Lim, Jeong A., Baek, Hye Jung, Jang, Moon Sun, Choi, Eun Kyoung, Lee, Yong Min, Lee, Sang Jin, Lim, Sung Chul, Kim, Joo Young, Kim, Tae Hyun, Kim, Hye Sun, Mishra, Lopa, Kim, Sang Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229887/
https://ncbi.nlm.nih.gov/pubmed/24064296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt222
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