Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland

Environmental and genetic factors exert important influences on lifespan and neoplastic transformation. We have previously shown that spontaneous tumors form frequently in mice homozygous for a full-length Brca1 deletion. In general, mutations of BRCA1 are closely associated with induction of breast...

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Vydáno v:Anal Cell Pathol (Amst)
Hlavní autoři: Kim, Sun Eui, Baek, Hye Jung, Park, Eun Jung, Lim, Sung Chul, Kim, Sang Soo
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311772/
https://ncbi.nlm.nih.gov/pubmed/30652068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8120579
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