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Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland

Environmental and genetic factors exert important influences on lifespan and neoplastic transformation. We have previously shown that spontaneous tumors form frequently in mice homozygous for a full-length Brca1 deletion. In general, mutations of BRCA1 are closely associated with induction of breast...

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Dettagli Bibliografici
Pubblicato in:Anal Cell Pathol (Amst)
Autori principali: Kim, Sun Eui, Baek, Hye Jung, Park, Eun Jung, Lim, Sung Chul, Kim, Sang Soo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311772/
https://ncbi.nlm.nih.gov/pubmed/30652068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8120579
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