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Hepatocellular Cancer Arises from Loss of Transforming Growth Factor Beta Signaling Adaptor Protein Embryonic Liver Fodrin Through Abnormal Angiogenesis
We have previously demonstrated that 40%–70% of elf(+/−) mice spontaneously develop hepatocellular cancer (HCC) within 15 months, revealing the importance of the transforming growth factor-beta (TGF-β) signaling pathway in suppressing tumorigenesis in the liver. The current study was carried out to...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747753/ https://ncbi.nlm.nih.gov/pubmed/18704924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22460 |
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