Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.

To elucidate the mechanism of recognition of double-stranded DNA (dsDNA) by homopyrimidine polyamide ("peptide") nucleic acid (PNA) leading to the strand-displacement, the kinetics of the sequence-specific PNA/DNA binding have been studied. The binding was monitored with time by the gel retardation...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Demidov, V V, Yavnilovich, M V, Belotserkovskii, B P, Frank-Kamenetskii, M D, Nielsen, P E
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2637
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!