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Peptide nucleic acid.DNA strand displacement loops as artificial transcription promoters.

Homopyrimidine peptide nucleic acids (PNAs) form loop structures when binding to complementary double-stranded DNA by strand displacement, and we now show that RNA polymerase recognizes these and initiates RNA transcription from PNA/double-stranded DNA strand displacement complexes at an efficiency...

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Autors principals: Møllegaard, N E, Buchardt, O, Egholm, M, Nielsen, P E
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC43688/
https://ncbi.nlm.nih.gov/pubmed/8171008
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