Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells

The roles of Argonaute proteins in cytoplasmic microRNA and RNAi pathways are well established. However, their implication in small RNA-mediated transcriptional gene silencing in the mammalian cell nucleus is less understood. We have recently shown that intronic siRNAs cause chromatin modifications...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Alló, Mariano, Agirre, Eneritz, Bessonov, Sergey, Bertucci, Paola, Gómez Acuña, Luciana, Buggiano, Valeria, Bellora, Nicolás, Singh, Babita, Petrillo, Ezequiel, Blaustein, Matías, Miñana, Belén, Dujardin, Gwendal, Pozzi, Berta, Pelisch, Federico, Bechara, Elías, Agafonov, Dmitry E., Srebrow, Anabella, Lührmann, Reinhard, Valcárcel, Juan, Eyras, Eduardo, Kornblihtt, Alberto R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226100/
https://ncbi.nlm.nih.gov/pubmed/25313066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416858111
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