Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells

The roles of Argonaute proteins in cytoplasmic microRNA and RNAi pathways are well established. However, their implication in small RNA-mediated transcriptional gene silencing in the mammalian cell nucleus is less understood. We have recently shown that intronic siRNAs cause chromatin modifications...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Alló, Mariano, Agirre, Eneritz, Bessonov, Sergey, Bertucci, Paola, Gómez Acuña, Luciana, Buggiano, Valeria, Bellora, Nicolás, Singh, Babita, Petrillo, Ezequiel, Blaustein, Matías, Miñana, Belén, Dujardin, Gwendal, Pozzi, Berta, Pelisch, Federico, Bechara, Elías, Agafonov, Dmitry E., Srebrow, Anabella, Lührmann, Reinhard, Valcárcel, Juan, Eyras, Eduardo, Kornblihtt, Alberto R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2014
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226100/
https://ncbi.nlm.nih.gov/pubmed/25313066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416858111
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