Nuclear role for human Argonaute-1 as an estrogen-dependent transcription coactivator

In mammals, argonaute (AGO) proteins have been characterized for their roles in small RNA–mediated posttranscriptional and also in transcriptional gene silencing. Here, we report a different role for AGO1 in estradiol-triggered transcriptional activation in human cells. We show that in MCF-7 mammary...

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Udgivet i:J Cell Biol
Main Authors: Gómez Acuña, Luciana I., Nazer, Ezequiel, Rodríguez-Seguí, Santiago A., Pozzi, Berta, Buggiano, Valeria, Marasco, Luciano E., Agirre, Eneritz, He, Cody, Alló, Mariano, Kornblihtt, Alberto R.
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2020
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480116/
https://ncbi.nlm.nih.gov/pubmed/32673398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201908097
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