Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-120 interface

The isolation of human monoclonal antibodies (mAbs) is providing important insights regarding the specificities that underlie broad neutralization of HIV-1 (reviewed in(1)). Here we report a broad and extremely potent HIV-specific mAb, termed 35O22, which binds novel HIV-1 envelope glycoprotein (Env...

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Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Huang, Jinghe, Kang, Byong H., Pancera, Marie, Lee, Jeong Hyun, Tong, Tommy, Feng, Yu, Georgiev, Ivelin S., Chuang, Gwo-Yu, Druz, Aliaksandr, Doria-Rose, Nicole A., Laub, Leo, Sliepen, Kwinten, van Gils, Marit J., de la Peña, Alba Torrents, Derking, Ronald, Klasse, Per-Johan, Migueles, Stephen A., Bailer, Robert T., Alam, Munir, Pugach, Pavel, Haynes, Barton F., Wyatt, Richard T., Sanders, Rogier W., Binley, James M., Ward, Andrew B., Mascola, John R., Kwong, Peter D., Connors, Mark
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224615/
https://ncbi.nlm.nih.gov/pubmed/25186731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13601
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