Загрузка...
A Germline Polymorphism of Thymine DNA Glycosylase Induces Genomic Instability and Cellular Transformation
Thymine DNA glycosylase (TDG) functions in base excision repair, a DNA repair pathway that acts in a lesion-specific manner to correct individual damaged or altered bases. TDG preferentially catalyzes the removal of thymine and uracil paired with guanine, and is also active on 5-fluorouracil (5-FU)...
Сохранить в:
| Опубликовано в: : | PLoS Genet |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222680/ https://ncbi.nlm.nih.gov/pubmed/25375110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004753 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|