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Mercaptopurine/Methotrexate Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia: Clinical Facts and Fiction

The antileukemic mechanisms of 6-mercaptopurine (6MP) and methotrexate (MTX) maintenance therapy are poorly understood, but the benefits of several years of myelosuppressive maintenance therapy for acute lymphoblastic leukemia are well proven. Currently, there is no international consensus on drug d...

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Bibliografski detalji
Izdano u:J Pediatr Hematol Oncol
Glavni autori: Schmiegelow, Kjeld, Nielsen, Stine N., Frandsen, Thomas L., Nersting, Jacob
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222610/
https://ncbi.nlm.nih.gov/pubmed/24936744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000206
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