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Mercaptopurine/Methotrexate Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia: Clinical Facts and Fiction

The antileukemic mechanisms of 6-mercaptopurine (6MP) and methotrexate (MTX) maintenance therapy are poorly understood, but the benefits of several years of myelosuppressive maintenance therapy for acute lymphoblastic leukemia are well proven. Currently, there is no international consensus on drug d...

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Podrobná bibliografie
Vydáno v:J Pediatr Hematol Oncol
Hlavní autoři: Schmiegelow, Kjeld, Nielsen, Stine N., Frandsen, Thomas L., Nersting, Jacob
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222610/
https://ncbi.nlm.nih.gov/pubmed/24936744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000206
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