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Mercaptopurine/Methotrexate Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia: Clinical Facts and Fiction

The antileukemic mechanisms of 6-mercaptopurine (6MP) and methotrexate (MTX) maintenance therapy are poorly understood, but the benefits of several years of myelosuppressive maintenance therapy for acute lymphoblastic leukemia are well proven. Currently, there is no international consensus on drug d...

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Dades bibliogràfiques
Publicat a:J Pediatr Hematol Oncol
Autors principals: Schmiegelow, Kjeld, Nielsen, Stine N., Frandsen, Thomas L., Nersting, Jacob
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222610/
https://ncbi.nlm.nih.gov/pubmed/24936744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000206
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