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Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia

Predicting the response to medical therapy and subsequently individualizing the treatment to increase efficacy or reduce toxicity has been a longstanding clinical goal. Not least within oncology, where many patients fail to be cured, and others are treated to or beyond the limit of acceptable toxici...

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Détails bibliographiques
Auteurs principaux: Nersting, Jacob, Borst, Louise, Schmiegelow, Kjeld
Format: Artigo
Langue:Inglês
Publié: Springer 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170275/
https://ncbi.nlm.nih.gov/pubmed/21906358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1559-0275-8-8
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