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A Conserved Acidic Residue in Phenylalanine Hydroxylase Contributes to Cofactor Affinity and Catalysis
[Image: see text] The catalytic domains of aromatic amino acid hydroxylases (AAAHs) contain a non-heme iron coordinated to a 2-His-1-carboxylate facial triad and two water molecules. Asp139 from Chromobacterium violaceum PAH (cPAH) resides within the second coordination sphere and contributes key hy...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biochemistry |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American
Chemical Society
2014
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222540/ https://ncbi.nlm.nih.gov/pubmed/25295853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500734h |
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