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An additional substrate binding site in a bacterial phenylalanine hydroxylase
Phenylalanine hydroxylase (PAH) is a non-heme iron enzyme that catalyzes phenylalanine oxidation to tyrosine, a reaction that must be kept under tight regulatory control. Mammalian PAH features a regulatory domain where binding of the substrate leads to allosteric activation of the enzyme. However,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972754/ https://ncbi.nlm.nih.gov/pubmed/23860686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-013-0919-8 |
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