Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial–mesenchymal transition

Pyruvate kinase M2 (PKM2) is an alternatively spliced variant of the pyruvate kinase gene that is preferentially expressed during embryonic development and in cancer cells. PKM2 alters the final rate-limiting step of glycolysis, resulting in the cancer-specific Warburg effect (also referred to as ae...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hamabe, Atsushi, Konno, Masamitsu, Tanuma, Nobuhiro, Shima, Hiroshi, Tsunekuni, Kenta, Kawamoto, Koichi, Nishida, Naohiro, Koseki, Jun, Mimori, Koshi, Gotoh, Noriko, Yamamoto, Hirofumi, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2014
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217454/
https://ncbi.nlm.nih.gov/pubmed/25313085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407717111
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