Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial–mesenchymal transition

Pyruvate kinase M2 (PKM2) is an alternatively spliced variant of the pyruvate kinase gene that is preferentially expressed during embryonic development and in cancer cells. PKM2 alters the final rate-limiting step of glycolysis, resulting in the cancer-specific Warburg effect (also referred to as ae...

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Detaylı Bibliyografya
Asıl Yazarlar: Hamabe, Atsushi, Konno, Masamitsu, Tanuma, Nobuhiro, Shima, Hiroshi, Tsunekuni, Kenta, Kawamoto, Koichi, Nishida, Naohiro, Koseki, Jun, Mimori, Koshi, Gotoh, Noriko, Yamamoto, Hirofumi, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217454/
https://ncbi.nlm.nih.gov/pubmed/25313085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407717111
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