Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming

Noncoding microRNAs inhibit translation and lower the transcript stability of coding mRNA, however miR-369 s, in aberrant silencing genomic regions, stabilizes target proteins under cellular stress. We found that in vitro differentiation of embryonic stem cells led to chromatin methylation of histon...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Konno, Masamitsu, Koseki, Jun, Kawamoto, Koichi, Nishida, Naohiro, Matsui, Hidetoshi, Dewi, Dyah Laksmi, Ozaki, Miyuki, Noguchi, Yuko, Mimori, Koshi, Gotoh, Noriko, Tanuma, Nobuhiro, Shima, Hiroshi, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503752/
https://ncbi.nlm.nih.gov/pubmed/26176628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132789
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