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Dynamic architecture of a protein kinase
Protein kinases are dynamically regulated signaling proteins that act as switches in the cell by phosphorylating target proteins. To establish a framework for analyzing linkages between structure, function, dynamics, and allostery in protein kinases, we carried out multiple microsecond-scale molecul...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217441/ https://ncbi.nlm.nih.gov/pubmed/25319261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418402111 |
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