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Protein Kinases: Evolution of Dynamic Regulatory Proteins
Eukaryotic protein kinases evolved as a family of highly dynamic molecules with strictly organized internal architecture. A single hydrophobic F-helix serves as a central scaffold for assembly of the entire molecule. Two non-consecutive hydrophobic structures termed “Spines” anchor all the elements...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3084033/ https://ncbi.nlm.nih.gov/pubmed/20971646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.09.006 |
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