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Defining the Conserved Internal Architecture of a Protein Kinase

Protein kinases constitute a large protein family of important regulators in all eukaryotic cells. All of the protein kinases have a similar bilobal fold, and their key structural features have been well studied. However, the recent discovery of non-contiguous hydrophobic ensembles inside the protei...

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Detalhes bibliográficos
Main Authors: Kornev, Alexandr P., Taylor, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435107/
https://ncbi.nlm.nih.gov/pubmed/19879387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.10.017
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