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Facilitated sequence counting and assembly by template mutagenesis
Presently, inferring the long-range structure of the DNA templates is limited by short read lengths. Accurate template counts suffer from distortions occurring during PCR amplification. We explore the utility of introducing random mutations in identical or nearly identical templates to create distin...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4217440/ https://ncbi.nlm.nih.gov/pubmed/25313059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416204111 |
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