Low load for disruptive mutations in autism genes and their biased transmission

We previously computed that genes with de novo (DN) likely gene-disruptive (LGD) mutations in children with autism spectrum disorders (ASD) have high vulnerability: disruptive mutations in many of these genes, the vulnerable autism genes, will have a high likelihood of resulting in ASD. Because indi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Iossifov, Ivan, Levy, Dan, Allen, Jeremy, Ye, Kenny, Ronemus, Michael, Lee, Yoon-ha, Yamrom, Boris, Wigler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611648/
https://ncbi.nlm.nih.gov/pubmed/26401017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516376112
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados