Загрузка...
Measuring shared variants in cohorts of discordant siblings with applications to autism
We develop a method of analysis [affected to discordant sibling pairs (A2DS)] that tests if shared variants contribute to a disorder. Using a standard measure of genetic relation, test individuals are compared with a cohort of discordant sibling pairs (CDS) to derive a comparative similarity score....
Сохранить в:
| Опубликовано в: : | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502605/ https://ncbi.nlm.nih.gov/pubmed/28630308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700439114 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|