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The capping enzyme facilitates promoter escape and assembly of a follow-on preinitiation complex for reinitiation
After synthesis of a short nascent RNA, RNA polymerase II (pol II) dissociates general transcription factors (GTFs; TFIIA, TFIIB, TBP, TFIIE, TFIIF, and TFIIH) and escapes the promoter, but many of the mechanistic details of this process remain unclear. Here we developed an in vitro transcription sy...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842614/ https://ncbi.nlm.nih.gov/pubmed/31591205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905449116 |
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