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Capping protein regulatory cycle driven by CARMIL and V-1 may promote actin network assembly at protruding edges

Although capping protein (CP) terminates actin filament elongation, it promotes Arp2/3-dependent actin network assembly and accelerates actin-based motility both in vitro and in vivo. In vitro, capping protein Arp2/3 myosin I linker (CARMIL) antagonizes CP by reducing its affinity for the barbed end...

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Detalhes bibliográficos
Main Authors: Fujiwara, Ikuko, Remmert, Kirsten, Piszczek, Grzegorz, Hammer, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024869/
https://ncbi.nlm.nih.gov/pubmed/24778263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313738111
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