Mechanism for CARMIL Protein Inhibition of Heterodimeric Actin-capping Protein

Capping protein (CP) controls the polymerization of actin filaments by capping their barbed ends. In lamellipodia, CP dissociates from the actin cytoskeleton rapidly, suggesting the possible existence of an uncapping factor, for which the protein CARMIL (capping protein, Arp2/3 and myosin-I linker)...

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Main Authors: Kim, Taekyung, Ravilious, Geoffrey E., Sept, David, Cooper, John A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346114/
https://ncbi.nlm.nih.gov/pubmed/22411988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.345447
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