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Direct Observation of the Uncapping of Capping Protein-capped Actin Filaments by CARMIL Homology Domain 3

Bulk solution assays have shown that the isolated CARMIL homology 3 (CAH3) domain from mouse and Acanthamoeba CARMIL rapidly and potently restores actin polymerization when added to actin filaments previously capped with capping protein (CP). To demonstrate this putative uncapping activity directly,...

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Autori principali: Fujiwara, Ikuko, Remmert, Kirsten, Hammer, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807327/
https://ncbi.nlm.nih.gov/pubmed/19926785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031203
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