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Capping protein regulatory cycle driven by CARMIL and V-1 may promote actin network assembly at protruding edges
Although capping protein (CP) terminates actin filament elongation, it promotes Arp2/3-dependent actin network assembly and accelerates actin-based motility both in vitro and in vivo. In vitro, capping protein Arp2/3 myosin I linker (CARMIL) antagonizes CP by reducing its affinity for the barbed end...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024869/ https://ncbi.nlm.nih.gov/pubmed/24778263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313738111 |
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