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The capping enzyme facilitates promoter escape and assembly of a follow-on preinitiation complex for reinitiation

After synthesis of a short nascent RNA, RNA polymerase II (pol II) dissociates general transcription factors (GTFs; TFIIA, TFIIB, TBP, TFIIE, TFIIF, and TFIIH) and escapes the promoter, but many of the mechanistic details of this process remain unclear. Here we developed an in vitro transcription sy...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fujiwara, Rina, Damodaren, Nivedita, Wilusz, Jeremy E., Murakami, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842614/
https://ncbi.nlm.nih.gov/pubmed/31591205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905449116
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