Wordt geladen...
Systematic Comparison of Molecular Conformations of H(+),K(+)-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating
Gastric H(+),K(+)-ATPase, an ATP-driven proton pump responsible for gastric acidification, is a molecular target for anti-ulcer drugs. Here we show its cryo-electron microscopy (EM) structure in an E2P analog state, bound to magnesium fluoride (MgF), and its K(+)-competitive antagonist SCH28080, det...
Bewaard in:
| Hoofdauteurs: | , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2014
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215238/ https://ncbi.nlm.nih.gov/pubmed/25231997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.584623 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|