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Inter-subunit interaction of gastric H(+),K(+)-ATPase prevents reverse reaction of the transport cycle

The gastric H(+),K(+)-ATPase is an ATP-driven proton pump responsible for generating a million-fold proton gradient across the gastric membrane. We present the structure of gastric H(+),K(+)-ATPase at 6.5 Å resolution as determined by electron crystallography of two-dimensional crystals. The structu...

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Detalhes bibliográficos
Main Authors: Abe, Kazuhiro, Tani, Kazutoshi, Nishizawa, Tomohiro, Fujiyoshi, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693145/
https://ncbi.nlm.nih.gov/pubmed/19387495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.102
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