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Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant

Acid-related gastric diseases are associated with disorder of digestive tract acidification. The gastric proton pump, H(+),K(+)-ATPase, exports H(+) in exchange for luminal K(+) to generate a highly acidic environment in the stomach, and is a main target for acid suppressants. Here, we report the th...

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Autors principals: Abe, Kazuhiro, Tani, Kazutoshi, Fujiyoshi, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105306/
https://ncbi.nlm.nih.gov/pubmed/21224846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1154
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