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Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant
Acid-related gastric diseases are associated with disorder of digestive tract acidification. The gastric proton pump, H(+),K(+)-ATPase, exports H(+) in exchange for luminal K(+) to generate a highly acidic environment in the stomach, and is a main target for acid suppressants. Here, we report the th...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105306/ https://ncbi.nlm.nih.gov/pubmed/21224846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1154 |
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