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Cryo-EM structure of gastric H(+),K(+)-ATPase with a single occupied cation-binding site
Gastric H(+),K(+)-ATPase is responsible for gastric acid secretion. ATP-driven H(+) uptake into the stomach is efficiently accomplished by the exchange of an equal amount of K(+), resulting in a luminal pH close to 1. Because of the limited free energy available for ATP hydrolysis, the stoichiometry...
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| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494912/ https://ncbi.nlm.nih.gov/pubmed/23091039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212294109 |
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