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Cholesterol Ester Oxidation by Mycobacterial Cytochrome P450

Mycobacteria share a common cholesterol degradation pathway initiated by oxidation of the alkyl side chain by enzymes of cytochrome P450 (CYP) families 125 and 142. Structural and sequence comparisons of the two enzyme families revealed two insertions into the N-terminal region of the CYP125 family...

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Detalhes bibliográficos
Main Authors: Frank, Daniel J., Madrona, Yarrow, Ortiz de Montellano, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215225/
https://ncbi.nlm.nih.gov/pubmed/25210044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602771
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