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1-Aminobenzotriazole: A Mechanism-Based Cytochrome P450 Inhibitor and Probe of Cytochrome P450 Biology

1-Aminobenzotriazole (1-ABT) is a pan-specific, mechanism-based inactivator of the xenobiotic metabolizing forms of cytochrome P450 in animals, plants, insects, and microorganisms. It has been widely used to investigate the biological roles of cytochrome P450 enzymes, their participation in the meta...

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Détails bibliographiques
Publié dans:Med Chem (Los Angeles)
Auteur principal: de Montellano, Paul R Ortiz
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137267/
https://ncbi.nlm.nih.gov/pubmed/30221034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0444.1000495
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