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1-Aminobenzotriazole: A Mechanism-Based Cytochrome P450 Inhibitor and Probe of Cytochrome P450 Biology

1-Aminobenzotriazole (1-ABT) is a pan-specific, mechanism-based inactivator of the xenobiotic metabolizing forms of cytochrome P450 in animals, plants, insects, and microorganisms. It has been widely used to investigate the biological roles of cytochrome P450 enzymes, their participation in the meta...

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Detalhes bibliográficos
Publicado no:Med Chem (Los Angeles)
Autor principal: de Montellano, Paul R Ortiz
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137267/
https://ncbi.nlm.nih.gov/pubmed/30221034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0444.1000495
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