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Cytochrome P450-activated prodrugs
A prodrug is a compound that has negligible, or lower, activity against a specified pharmacological target than one of its major metabolites. Prodrugs can be used to improve drug delivery or pharmacokinetics, to decrease toxicity, or to target the drug to specific cells or tissues. Ester and phospha...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3697796/ https://ncbi.nlm.nih.gov/pubmed/23360144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.197 |
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