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1-Aminobenzotriazole: A Mechanism-Based Cytochrome P450 Inhibitor and Probe of Cytochrome P450 Biology

1-Aminobenzotriazole (1-ABT) is a pan-specific, mechanism-based inactivator of the xenobiotic metabolizing forms of cytochrome P450 in animals, plants, insects, and microorganisms. It has been widely used to investigate the biological roles of cytochrome P450 enzymes, their participation in the meta...

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Publicat a:Med Chem (Los Angeles)
Autor principal: de Montellano, Paul R Ortiz
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137267/
https://ncbi.nlm.nih.gov/pubmed/30221034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0444.1000495
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