Pro-Regenerative Signaling after Acetaminophen-Induced Acute Liver Injury in Mice Identified Using a Novel Incremental Dose Model

Acetaminophen (APAP) overdose results in acute liver failure and has limited treatment options. Previous studies show that stimulating liver regeneration is critical for survival after APAP overdose, but the mechanisms remain unclear. In this study, we identified major signaling pathways involved in...

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書誌詳細
主要な著者: Bhushan, Bharat, Walesky, Chad, Manley, Michael, Gallagher, Tara, Borude, Prachi, Edwards, Genea, Monga, Satdarshan P.S., Apte, Udayan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2014
主題:
Regular Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215032/
https://ncbi.nlm.nih.gov/pubmed/25193591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.07.019
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