Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy

Diabetes is associated with activation of the polyol pathway, in which glucose is converted to sorbitol by aldose reductase. Previous studies focused on the role of sorbitol in mediating diabetic complications. However, in the proximal tubule, sorbitol can be converted to fructose, which is then met...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lanaspa, Miguel A., Ishimoto, Takuji, Cicerchi, Christina, Tamura, Yoshifuru, Roncal-Jimenez, Carlos A., Chen, Wei, Tanabe, Katsuyuki, Andres-Hernando, Ana, Orlicky, David J., Finol, Esteban, Inaba, Shinichiro, Li, Nanxing, Rivard, Christopher J., Kosugi, Tomoki, Sanchez-Lozada, Laura G., Petrash, J. Mark, Sautin, Yuri Y., Ejaz, A. Ahsan, Kitagawa, Wataru, Garcia, Gabriela E., Bonthron, David T., Asipu, Aruna, Diggle, Christine P., Rodriguez-Iturbe, Bernardo, Nakagawa, Takahiko, Johnson, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2014
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214522/
https://ncbi.nlm.nih.gov/pubmed/24876114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080901
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars