Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice

Fructose intake from added sugars correlates with the epidemic rise in obesity, metabolic syndrome, and nonalcoholic fatty liver disease. Fructose intake also causes features of metabolic syndrome in laboratory animals and humans. The first enzyme in fructose metabolism is fructokinase, which exists...

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Главные авторы: Ishimoto, Takuji, Lanaspa, Miguel A., Le, MyPhuong T., Garcia, Gabriela E., Diggle, Christine P., MacLean, Paul S., Jackman, Matthew R., Asipu, Aruna, Roncal-Jimenez, Carlos A., Kosugi, Tomoki, Rivard, Christopher J., Maruyama, Shoichi, Rodriguez-Iturbe, Bernardo, Sánchez-Lozada, Laura G., Bonthron, David T., Sautin, Yuri Y., Johnson, Richard J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306692/
https://ncbi.nlm.nih.gov/pubmed/22371574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119908109
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