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Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice

Fructose intake from added sugars correlates with the epidemic rise in obesity, metabolic syndrome, and nonalcoholic fatty liver disease. Fructose intake also causes features of metabolic syndrome in laboratory animals and humans. The first enzyme in fructose metabolism is fructokinase, which exists...

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Detalhes bibliográficos
Main Authors: Ishimoto, Takuji, Lanaspa, Miguel A., Le, MyPhuong T., Garcia, Gabriela E., Diggle, Christine P., MacLean, Paul S., Jackman, Matthew R., Asipu, Aruna, Roncal-Jimenez, Carlos A., Kosugi, Tomoki, Rivard, Christopher J., Maruyama, Shoichi, Rodriguez-Iturbe, Bernardo, Sánchez-Lozada, Laura G., Bonthron, David T., Sautin, Yuri Y., Johnson, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306692/
https://ncbi.nlm.nih.gov/pubmed/22371574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119908109
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