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RRHP: a tag-based approach for 5-hydroxymethylcytosine mapping at single-site resolution
Current methods for genomic mapping of 5-hydroxymethylcytosine (5hmC) have been limited by either costly sequencing depth, high DNA input, or lack of single-base resolution. We present an approach called Reduced Representation 5-Hydroxymethylcytosine Profiling (RRHP) to map 5hmC sites at single-base...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4212096/ https://ncbi.nlm.nih.gov/pubmed/25248841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0456-5 |
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