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A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution

Since the discovery of oxidative demethylation of methylcytosine (mC) by Tet enzymes, an analytical method has been urgently needed that would enable the identification of mC and hydroxymethylcytosine (hmC) at the single base resolution level, because their roles in gene regulation are quite differe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Kawasaki, Yuki, Kuroda, Yukiko, Suetake, Isao, Tajima, Shoji, Ishino, Fumitoshi, Kohda, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389479/
https://ncbi.nlm.nih.gov/pubmed/28204635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw994
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