Loading...
Single-CpG resolution mapping of 5-hydroxymethylcytosine by chemical labeling and exonuclease digestion identifies evolutionarily unconserved CpGs as TET targets
Conventional techniques for single-base resolution mapping of epigenetic modifications of DNA such as 5-hydroxymethylcytosine (5hmC) rely on the sequencing of bisulfite-modified DNA. Here we present an alternative approach called SCL-exo which combines selective chemical labeling (SCL) of 5hmC in ge...
Na minha lista:
| Udgivet i: | Genome Biol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2016
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810514/ https://ncbi.nlm.nih.gov/pubmed/27025842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0919-y |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|