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No CpGs for AAVs?
In this issue of Blood, Konkle et al report that 7 of 8 participants in a phase 1/2 trial of adeno-associated virus (AAV) vector (BAX335) for factor IX (FIX)-Padua gene transfer in patients with hemophilia B did not maintain expression despite steroid intervention, which the authors hypothesize is a...
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| Pubblicato in: | Blood |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885819/ https://ncbi.nlm.nih.gov/pubmed/33570612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009285 |
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